A person has died after a car and motorbike crashed on State Highway 29 near the Kaimai-Mamaku Forest Park.
Police said they were called to the crash near Hanga Road and Rapurapa Road shortly before 4pm.
Motorists should expect the road to be closed for some time, they said.
St John said two people with moderate injuries have been taken to Waikato Hospital.
In a separate accident, a person has died after a two car crash in Waihau Bay in Bay of Plenty.
Two ambulances and a rescue helicopter attended the crash but one person died at the scene, St John said.